SCHEMBL13668239

SCHEMBL13668239

CC(=O)c1ccc2c(c1)C1(CO2)COc2ccc(C(C)=O)cc21

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
RARB P10826 4/20 0.47
RARG P13631 4/20 0.47
RARA P10276 3/20 0.47
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MAPT P10636 1/20 0.44
AKR1B1 P15121 1/20 0.44
RXRA P19793 1/20 0.43
PTGS1 P23219 2/20 0.43
PTGS2 P35354 2/20 0.43
PRKCI P41743 1/20 0.41
HSD17B1 P14061 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PDK2 Q15119 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13668254 0.86 KDM4E (0.50) KDM4ERARBRARGRARANPC1
SCHEMBL3547915 0.85 RARB (0.63) KDM4ERARBRARGRARANPC1
SCHEMBL13668349 0.84 ALDH1A1 (0.53) KDM4ERARBRARGRARAMAPT
SCHEMBL13668316 0.83 TSHR (0.45) KDM4ERARBRARGRARANPC1
SCHEMBL13668324 0.83 NPC1 (0.49) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL13668358 0.83 RARB (0.41) KDM4ERARBRARGRARANPC1
SCHEMBL13668317 0.82 KMT2A (0.47) RARBRARGNPC1RAB9AMAPT
SCHEMBL13668312 0.82 HPGD (0.41) KDM4ERARBRARGRARANPC1
SCHEMBL13668323 0.78 CASP3 (0.50) KDM4ERARBRARGRARANPC1
SCHEMBL9142407 0.76 KDM4E (0.63) KDM4ENPC1RAB9AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7608309-B2 Resin composition, film and image display device utilizing the resin composition FUJIFILM CORPORATION (JP) 2009-10-27 US disclosed
US-7608309-B2 Resin composition, film and image display device utilizing the resin composition FUJIFILM CORPORATION (JP) 2009-10-27 US disclosed