SCHEMBL13669352

SCHEMBL13669352

c1ccc(-c2c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccc(-c5ccc6ccccc6c5)cc4)cc3c(-c3ccccc3)c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccc(-c5ccc6ccccc6c5)cc4)cc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ESR1 P03372 6/20 0.38
ESR2 Q92731 6/20 0.38
KMT2A Q03164 1/20 0.37
TSPO P30536 1/20 0.37
HDAC4 P56524 1/20 0.37
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12571840 1.00 KDM4E (0.42) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL11910822 1.00 KDM4E (0.42) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL19296453 0.99 KDM4E (0.44) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL15603762 0.97 KDM4E (0.41) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL262156 0.97 KDM4E (0.45) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL13433162 0.97 KDM4E (0.45) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL13433163 0.97 KDM4E (0.45) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL11910781 0.97 ESR1 (0.40) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL13433010 0.97 KDM4E (0.45) KDM4EATML3MBTL1ESR1ESR2
SCHEMBL124862 0.97 KDM4E (0.45) KDM4EATML3MBTL1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090267498-A1 Anthracene Derivative, Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-10-29 US disclosed
WO-2009131199-A1 ANTHRACENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPLIANCE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090267498-A1 Anthracene Derivative, Light-Emitting Element, Light-Emitting Device, and Electronic Appliance AP2A1, ABCE1, SLC35E1 KDM4E 2359/4885ATM 866/4885L3MBTL1 2011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.