⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28956079 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL25423053 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL30138123 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL9748897 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL8225575 | 0.72 | — | — | |
| SCHEMBL10568538 | 0.69 | LMNA (0.43) | — | |
| SCHEMBL3098037 | 0.69 | — | — | |
| SCHEMBL16401862 | 0.67 | — | — | |
| SCHEMBL28472 | 0.67 | — | — | |
| SCHEMBL25204917 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605151-B2 | angiogenesis inhibitor; antiinflammatory agents; immunosuppressants; steroids conjugated compound | NICOX S.A. (FR) | 2009-10-20 | — | — | US | disclosed |
| US-20080234242-A1 | NITRATE ESTERS OF CORTICOID COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | NICOX S.A. (FR) | 2008-09-25 | — | — | US | disclosed |
| US-7368442-B2 | Nitrate esters of corticoid compounds and pharmaceutical applications thereof | NICOX S.A. (FR) | 2008-05-06 | — | — | US | disclosed |
| US-20070161612-A1 | Nitrate esters of corticoid compounds and pharmaceutical applications thereof | NICOX S.A. | 2007-07-12 | — | — | US | disclosed |
| US-7205288-B2 | Nitrate esters of corticoid compounds and pharmaceutical applications thereof | NICOX S.A. (FR) | 2007-04-17 | — | — | US | disclosed |
| US-7160871-B2 | Nitrate esters of corticoid compounds and pharmaceutical applications thereof | NICOX S.A. (FR) | 2007-01-09 | — | — | US | disclosed |
| US-7157450-B2 | Nitrate esters of corticoid compounds and pharmaceutical applications thereof | NICOX S.A. (FR) | 2007-01-02 | — | — | US | disclosed |