Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662711 | 0.85 | MAOA (0.57) | VCPMAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL13321381 | 0.85 | VCP (0.49) | VCPMAOAMAOBKDM1AHTR1D | |
| Hydrochloric Acid SCHEMBL4799055 | 0.84 | MAOA (0.55) | VCPMAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL14862724 | 0.82 | MAOA (0.54) | VCPMAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL31706160 | 0.82 | MAOA (0.54) | VCPMAOAMAOBKDM1AHRH3 | |
| SCHEMBL13300917 | 0.81 | HRH3 (0.47) | VCPMAOAMAOBKDM1AHTR1D | |
| SCHEMBL8778016 | 0.81 | HPGD (0.55) | MAOAMAOBKDM1AHRH3ALDH1A1 | |
| SCHEMBL5863593 | 0.81 | HPGD (0.55) | MAOAMAOBKDM1AHRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16464069 | 0.81 | MAOA (0.53) | VCPMAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL25103815 | 0.79 | HRH3 (0.47) | VCPMAOAMAOBKDM1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009121063-A2 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2009-10-01 | — | — | WO | disclosed |