Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13670533 | 0.68 | MAPT (0.32) | ALDH1A1MAPT | |
| SCHEMBL6568773 | 0.65 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL29870751 | 0.65 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL516020 | 0.65 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL5612358 | 0.65 | SIGMAR1 (0.48) | SIGMAR1L3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL13511256 | 0.64 | SIGMAR1 (0.41) | SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL5423604 | 0.64 | SIGMAR1 (0.50) | SIGMAR1L3MBTL1ALDH1A1KMT2ATSHR | |
| SCHEMBL13304304 | 0.63 | HPGD (0.38) | SIGMAR1L3MBTL1ALDH1A1KDM4EKMT2A | |
| SCHEMBL4888596 | 0.62 | SIGMAR1 (0.48) | SIGMAR1L3MBTL1ALDH1A1LMNAKDM4E | |
| SCHEMBL272955 | 0.62 | SIGMAR1 (0.51) | SIGMAR1L3MBTL1ALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118087-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2009-10-01 | — | — | WO | disclosed |