Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568773 | 1.00 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL516020 | 1.00 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR | |
| Boric Acid SCHEMBL29084632 | 0.91 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL9934401 | 0.89 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL29627309 | 0.89 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL5423604 | 0.87 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL6314684 | 0.87 | ALDH1A1 (0.58) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL13321032 | 0.87 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL18134972 | 0.87 | CYP2A6 (0.58) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL12636587 | 0.87 | SIGMAR1 (0.49) | SIGMAR1ALDH1A1HSD17B10CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11421924-B2 | Heat transfer circuit with targeted additive supply | TRANE INTERNATIONAL INC. (US) | 2022-08-23 | — | — | US | claimed |
| US-11421924-B2 | Heat transfer circuit with targeted additive supply | TRANE INTERNATIONAL INC. (US) | 2022-08-23 | — | — | US | disclosed |