SCHEMBL13672802

SCHEMBL13672802

CCC(C)(O)C(=O)c1ccc(C(=O)c2ccc(C(=O)C(C)(C)O)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.40
ALDH1A1 P00352 3/20 0.40
SRD5A2 P31213 3/20 0.40
LMNA P02545 2/20 0.40
MLYCD O95822 2/20 0.38
HPGD P15428 3/20 0.37
MAPT P10636 2/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
PKM P14618 1/20 0.37
HTT P42858 1/20 0.37
SIRT1 Q96EB6 1/20 0.36
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419639 0.88 ALDH1A1 (0.50) ELANEALDH1A1SRD5A2LMNAHPGD
SCHEMBL10945363 0.87 ALDH1A1 (0.52) ELANEALDH1A1SRD5A2LMNAHPGD
SCHEMBL4083719 0.85 KMT2A (0.47) ELANEALDH1A1SRD5A2LMNAMLYCD
SCHEMBL5454029 0.84 HPGD (0.46) ELANEALDH1A1HPGDMAPTHTT
SCHEMBL10948069 0.83 ALDH1A1 (0.52) ALDH1A1SRD5A2LMNAHPGDMAPT
SCHEMBL11298330 0.81 CA2 (0.46) ELANEALDH1A1SRD5A2LMNAMLYCD
SCHEMBL30912032 0.81 SRD5A2 (0.53) ELANEALDH1A1SRD5A2LMNAHPGD
SCHEMBL10941227 0.80 ALDH1A1 (0.67) ALDH1A1SRD5A2LMNAHPGDMAPT
SCHEMBL4468555 0.80 CA2 (0.55) ALDH1A1SRD5A2LMNAHPGDMAPT
SCHEMBL10941702 0.80 ALDH1A1 (0.58) ELANEALDH1A1SRD5A2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1930309-B1 Preparation of alpha-hydroxyketones BASF SE (DE) 2009-10-21 EP disclosed