Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31512115 | 0.85 | — | — | |
| SCHEMBL19908503 | 0.82 | KDM5A (0.30) | — | |
| SCHEMBL22158339 | 0.79 | TSHR (0.32) | TSHR | |
| SCHEMBL22158342 | 0.76 | TSHR (0.39) | TSHR | |
| SCHEMBL14000488 | 0.74 | CYP1A2 (0.47) | ALDH1A1TSHRCYP1A2CYP2D6DNM1 | |
| SCHEMBL18469094 | 0.74 | DNM1 (0.48) | ALDH1A1TSHRCYP1A2CYP2D6DNM1 | |
| SCHEMBL24246387 | 0.73 | — | — | |
| SCHEMBL8037915 | 0.73 | — | — | |
| SCHEMBL3651929 | 0.73 | DNM1 (0.52) | ALDH1A1TSHRCYP1A2CYP2D6DNM1 | |
| SCHEMBL29172219 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP1A2CYP2D6DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605261-B2 | Urea derivatives, method for preparing same, use thereof as medicines, pharmaceutical compositions and novel use | AMGEN INC. (US) | 2009-10-20 | — | — | US | disclosed |