Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 13/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13672907 | 0.91 | IL1B (0.48) | IL1BP2RX7KMT2ANPC1 | |
| SCHEMBL1019477 | 0.89 | IL1B (0.62) | IL1BP2RX7 | |
| SCHEMBL1020293 | 0.89 | IL1B (0.49) | IL1BP2RX7KMT2AMEN1ALDH1A1 | |
| SCHEMBL12955034 | 0.84 | P2RX7 (0.49) | IL1BP2RX7KMT2AMEN1NPC1 | |
| SCHEMBL11955051 | 0.82 | P2RX7 (0.53) | IL1BP2RX7 | |
| SCHEMBL12955002 | 0.81 | P2RX7 (0.53) | IL1BP2RX7KMT2AMEN1NPC1 | |
| SCHEMBL12955006 | 0.81 | P2RX7 (0.53) | IL1BP2RX7KMT2AMEN1NPC1 | |
| SCHEMBL13673004 | 0.81 | IL1B (0.42) | IL1BP2RX7 | |
| SCHEMBL13672898 | 0.80 | P2RX7 (0.51) | IL1BP2RX7KMT2ANPC1 | |
| SCHEMBL11954745 | 0.80 | P2RX7 (0.57) | IL1BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118175-A1 | NOVEL P2X7R ANTAGONISTS AND THEIR USE | AFFECTIS PHARMACEUTICALS AG (DE) | 2009-10-01 | — | — | WO | disclosed |