Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | GNPAT | O15228 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13654776 | 0.96 | CA2 (0.58) | CA2CA4GNPATEPHX2FOLH1 | |
| SCHEMBL4572556 | 0.96 | CA2 (0.58) | CA2CA4GNPATEPHX2FOLH1 | |
| SCHEMBL10804103 | 0.87 | CA2 (0.55) | CA2CA4GNPATEPHX2FOLH1 | |
| SCHEMBL11279926 | 0.87 | CA2 (0.55) | CA2CA4GNPATEPHX2FOLH1 | |
| SCHEMBL4572562 | 0.87 | CA2 (0.55) | CA2CA4GNPATEPHX2FOLH1 | |
| SCHEMBL12426671 | 0.87 | CA2 (0.55) | CA2CA4GNPATEPHX2FOLH1 | |
| SCHEMBL14088908 | 0.87 | CA2 (0.55) | CA2CA4GNPATEPHX2FOLH1 | |
| SCHEMBL4572564 | 0.86 | CA2 (0.62) | CA2CA4EPHX2FOLH1RIMKLA | |
| SCHEMBL28885652 | 0.86 | CA2 (0.53) | CA2CA4GNPATEPHX2MME | |
| SCHEMBL30825659 | 0.86 | EPHX2 (0.55) | CA2CA4GNPATEPHX2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7597882-B2 | Protein crosslinkers, crosslinking methods and applications thereof | INCEPT LLC (US) | 2009-10-06 | — | — | US | disclosed |
| US-20070248567-A1 | Protein crosslinkers, crosslinking methods and applications thereof | AUGMENIX, INC. | 2007-10-25 | — | — | US | disclosed |