Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13674874 | 0.81 | F10 (0.44) | F10TBK1PIK3CD | |
| SCHEMBL3556995 | 0.81 | F10 (0.42) | F10TBK1JAK2PIK3CD | |
| SCHEMBL13672295 | 0.80 | F10 (0.47) | F10 | |
| SCHEMBL3556991 | 0.78 | F10 (0.43) | F10TBK1JAK2PIK3CD | |
| Trifluoroacetic Acid SCHEMBL4492676 | 0.77 | F10 (0.44) | F10 | |
| SCHEMBL4638729 | 0.76 | F10 (0.45) | F10PIK3CD | |
| SCHEMBL3551807 | 0.71 | PIK3CD (0.50) | F10TBK1PIK3CD | |
| SCHEMBL4639953 | 0.71 | PIK3CD (0.46) | F10JAK2PIK3CD | |
| SCHEMBL76130 | 0.71 | F10 (0.57) | F10 | |
| SCHEMBL76156 | 0.71 | F10 (0.57) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601752-B2 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-10-13 | — | — | US | disclosed |