Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4638732 | 0.81 | PIK3CD (0.43) | F10PIK3CD | |
| Trifluoroacetic Acid SCHEMBL4638725 | 0.78 | PIK3CD (0.42) | F10PIK3CD | |
| SCHEMBL3556995 | 0.77 | F10 (0.42) | F10PIK3CD | |
| SCHEMBL13675147 | 0.76 | F10 (0.41) | F10PIK3CD | |
| SCHEMBL3551807 | 0.75 | PIK3CD (0.50) | F10PIK3CDKDM4ESMN1; SMN2 | |
| SCHEMBL13674874 | 0.75 | F10 (0.44) | F10PIK3CD | |
| SCHEMBL3556991 | 0.75 | F10 (0.43) | F10PIK3CD | |
| SCHEMBL4639953 | 0.75 | PIK3CD (0.46) | F10PIK3CD | |
| SCHEMBL4638999 | 0.72 | ABCC9 (0.44) | F10 | |
| SCHEMBL6814419 | 0.71 | ABCC9 (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951717-A1 | NOVEL PYRROLIDINE DERIVATIVES AS INHIBITORS OF COAGULATION FACTOR XA | F.HOFFMANN-LA ROCHE AG (CH) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057317-A1 | NOVEL PYRROLIDINE DERIVATIVES AS INHIBITORS OF COAGULATION FACTOR XA | F. HOFFMANN-LA ROCHE AG (CH) | 2007-05-24 | — | — | WO | disclosed |