SCHEMBL13675360

SCHEMBL13675360

CCc1cccc(CNCCN2CCCCC2)c1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.65
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
APP P05067 2/20 0.52
SIGMAR1 Q99720 1/20 0.51
KMT2A Q03164 1/20 0.48
MAP4K4 O95819 1/20 0.47
TRPC5 Q9UL62 1/20 0.46
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
PARP1 P09874 1/20 0.46
HRH3 Q9Y5N1 1/20 0.44
CXCR4 P61073 1/20 0.43
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13186207 0.86 L3MBTL1 (0.53) DPP7KDM4EALDH1A1SMN1; SMN2APP
SCHEMBL15587390 0.84 DPP7 (0.67) DPP7KDM4EAPPSIGMAR1KMT2A
Hydrochloric Acid SCHEMBL5754522 0.81 DPP7 (0.63) DPP7ALDH1A1APPSIGMAR1DRD2
SCHEMBL8883456 0.81 DPP7 (0.96) DPP7APPSIGMAR1KMT2A
Hydrochloric Acid SCHEMBL5758122 0.81 KDM4E (0.62) DPP7KDM4EALDH1A1APPSIGMAR1
SCHEMBL13724011 0.81 DPP7 (0.67) DPP7SIGMAR1DRD2DRD4
SCHEMBL17896305 0.80 DPP7 (0.61) DPP7APPSIGMAR1KMT2AMAP4K4
Hydrochloric Acid SCHEMBL5759171 0.80 DPP7 (0.93) DPP7APPSIGMAR1KMT2A
Hydrochloric Acid SCHEMBL5758454 0.80 DPP7 (0.93) DPP7APPSIGMAR1KMT2A
Hydrochloric Acid SCHEMBL5756767 0.79 DPP7 (0.65) DPP7SIGMAR1DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090270381-A1 Non-steroidal progesterone receptor modulators BAYER SCHERING PHARMA AG (DE) 2009-10-29 US disclosed
WO-2009077186-A1 NONSTEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AKTIENGESLLSCHAFT (DE) 2009-06-25 WO disclosed
EP-2070909-A1 Non-steroidal progesterone receptor modulators Bayer Schering Pharma AG (DE) 2009-06-17 EP disclosed
US-20090075989-A1 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AG (DE) 2009-03-19 US disclosed
WO-2008077646-A1 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270381-A1 Non-steroidal progesterone receptor modulators PGR, PGRMC1, PGRMC2 DPP7 4618/4885KDM4E 992/4885ALDH1A1 1257/4885
US-20090075989-A1 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS NR5A1, CYP19A1, GPER1 DPP7 4716/4885KDM4E 1525/4885ALDH1A1 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.