Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGIR | P43119 | 2/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675578 | 0.93 | MEN1 (0.48) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL3937799 | 0.88 | KMT2A (0.63) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL394043 | 0.85 | SMN1; SMN2 (0.58) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL394034 | 0.85 | KMT2A (0.48) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL13675372 | 0.85 | MEN1 (0.46) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL394333 | 0.84 | MEN1 (0.48) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL3945526 | 0.84 | GAA (0.53) | MEN1KMT2APTGIRPTGDRKDM4E | |
| SCHEMBL3943891 | 0.83 | MEN1 (0.44) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL13676208 | 0.83 | KMT2A (0.60) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL3947728 | 0.83 | MEN1 (0.48) | MEN1KMT2AHTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230095836-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | FMC CORPORATION | 2023-03-30 | — | — | US | claimed |
| EP-4103554-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | FMC CORPORATION (US) | 2022-12-21 | — | — | EP | claimed |
| CN-115087639-A | Substituted 5, 6-diphenyl-3 (2H) -pyridazinones for use as fungicides | FMC公司 | 2022-09-20 | — | — | CN | claimed |
| WO-2021163519-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | FMC CORPORATION (US) | 2021-08-19 | — | — | WO | claimed |
| US-20230095836-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | FMC CORPORATION | 2023-03-30 | — | — | US | disclosed |
| EP-4103554-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | FMC CORPORATION (US) | 2022-12-21 | — | — | EP | disclosed |
| CN-115087639-A | Substituted 5, 6-diphenyl-3 (2H) -pyridazinones for use as fungicides | FMC公司 | 2022-09-20 | — | — | CN | disclosed |
| WO-2021163519-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | FMC CORPORATION (US) | 2021-08-19 | — | — | WO | disclosed |
| US-20090270399-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | KOWA CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
| US-20090069332-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | KOWA CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20080119474-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | KOWA CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270399-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | IL1B, IL1R1, TLR1 | MEN1 4730/4885KMT2A 3265/4885HTT 3839/4885 |
| US-20230095836-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | PNPO, CBR3, CYP2D6 | MEN1 2413/4885KMT2A 3432/4885HTT 4604/4885 |
| US-20090069332-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | IL1B, IL1R1, TLR1 | MEN1 4730/4885KMT2A 3265/4885HTT 3839/4885 |
| US-20080119474-A1 | NOVEL PYRIDAZINE DERIVATIVES AND MEDICINES CONTAINING THE SAME AS EFFECTIVE INGREDIENTS | IL1B, IL1R1, TLR1 | MEN1 4721/4885KMT2A 3295/4885HTT 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.