⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13575584 | 0.75 | SUV39H2 (0.30) | — | |
| SCHEMBL16866784 | 0.75 | — | — | |
| SCHEMBL29458366 | 0.71 | CA2 (0.30) | — | |
| SCHEMBL13656403 | 0.69 | ALDH1A1 (0.45) | — | |
| SCHEMBL21906271 | 0.69 | TSHR (0.46) | — | |
| SCHEMBL12207861 | 0.69 | — | — | |
| SCHEMBL20019698 | 0.66 | CA12 (0.33) | — | |
| SCHEMBL21906289 | 0.66 | MEN1 (0.36) | — | |
| SCHEMBL4359921 | 0.66 | — | — | |
| SCHEMBL16906617 | 0.65 | MEN1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206209-A1 | DEUTERATED COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Ascentawits Pharmaceuticals, Ltd. (CN) | 2023-07-05 | — | — | EP | disclosed |
| EP-1167972-B1 | Enzyme catalyzed therapeutic agents | KIADIS PHARMA INTELLECTUAL PROPERTY B V (NL) | 2017-03-08 | — | — | EP | disclosed |
| US-9226932-B2 | Phosphoramidate alkylator prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-20140170240-A1 | Phosphoramidate Alkylator Prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| US-8664204-B2 | Phosphoramidate alkylator prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-20130303778-A1 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | THRESHOLD PHARMACEUTICALS, INC. | 2013-11-14 | — | — | US | disclosed |
| US-8507464-B2 | Phosphoramidate alkylator prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-7601703-B2 | Enzyme catalyzed therapeutic agents | CELMED ONCOLOGY (USA), INC. (CA) | 2009-10-13 | — | — | US | disclosed |