Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 5/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17479930 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4PLA2G1B | |
| SCHEMBL17479940 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4PLA2G1B | |
| SCHEMBL17479936 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4PLA2G1B | |
| SCHEMBL2554287 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4PLA2G1B | |
| SCHEMBL17479928 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4PLA2G1B | |
| SCHEMBL17479929 | 1.00 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4PLA2G1B | |
| Hydrochloric Acid SCHEMBL27761815 | 0.98 | S1PR2 (0.53) | S1PR2S1PR1S1PR3S1PR4PLA2G1B | |
| SCHEMBL13675433 | 0.98 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR4PLA2G1B | |
| SCHEMBL14143218 | 0.98 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR4PLA2G1B | |
| SCHEMBL8227678 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | PKD2, PKD1, AADAT | S1PR2 3004/4885S1PR1 3437/4885S1PR3 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.