SCHEMBL13675433

SCHEMBL13675433

CCCCCC(N)CNC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 5/20 0.52
S1PR1 P21453 5/20 0.52
S1PR3 Q99500 5/20 0.52
S1PR4 O95977 4/20 0.52
OPRM1 P35372 1/20 0.48
PLA2G1B P04054 1/20 0.47
PLA2G2A P14555 1/20 0.47
SPHK1 Q9NYA1 2/20 0.40
TP53 P04637 2/20 0.39
LAP3 P28838 2/20 0.39
EPHX1 P07099 1/20 0.39
CYP2D6 P10635 2/20 0.38
GMNN O75496 1/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14143218 1.00 S1PR2 (0.52) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL17479940 0.98 S1PR2 (0.55) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL2554287 0.98 S1PR2 (0.55) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL13675450 0.98 S1PR2 (0.55) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL17479936 0.98 S1PR2 (0.55) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL17479929 0.98 S1PR2 (0.55) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL17479930 0.98 S1PR2 (0.55) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL17479928 0.98 S1PR2 (0.55) S1PR2S1PR1S1PR3S1PR4OPRM1
Hydrochloric Acid SCHEMBL27761815 0.96 S1PR2 (0.53) S1PR2S1PR1S1PR3S1PR4OPRM1
SCHEMBL8227678 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11471375-B2 Pulse oximetry-based cardio-pulmonary resuscitation (CPR) quality feedback systems and methods Peking Union Medical College Hospital (CN) 2022-10-18 US disclosed
US-11351265-B2 Process for formulating an anionic agent DICERNA PHARMACEUTICALS, INC. (US) 2022-06-07 US disclosed
US-20210292303-A1 AMINE CATIONIC LIPIDS AND USES THEREOF DICERNA PHARMACEUTICALS, INC. 2021-09-23 US disclosed
US-20190151461-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT DICERNA PHARMACEUTICALS, INC. (US) 2019-05-23 US disclosed
US-20090247519-A1 AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11351265-B2 Process for formulating an anionic agent PHOSPHO1, POLRMT, LIPA S1PR2 549/4885S1PR1 567/4885S1PR3 794/4885
US-20190151461-A1 PROCESS FOR FORMULATING AN ANIONIC AGENT PHOSPHO1, POLRMT, LIPA S1PR2 549/4885S1PR1 567/4885S1PR3 794/4885
US-20210292303-A1 AMINE CATIONIC LIPIDS AND USES THEREOF SGMS2, SLC43A1, SGMS1 S1PR2 166/4885S1PR1 222/4885S1PR3 160/4885
US-20090247519-A1 AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE PKD2, PKD1, AADAT S1PR2 3004/4885S1PR1 3437/4885S1PR3 2272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.