Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637391 | 1.00 | HSD11B1 (0.50) | HSD11B1NR1H3 | |
| SCHEMBL26303466 | 0.94 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL10165226 | 0.82 | HSD11B1 (0.59) | HSD11B1NR1H3 | |
| SCHEMBL5402087 | 0.80 | HSD11B1 (0.46) | HSD11B1NR1H3 | |
| SCHEMBL3278683 | 0.79 | NR1H2 (0.50) | NR1H3 | |
| SCHEMBL14653580 | 0.79 | PDE2A (0.47) | — | |
| SCHEMBL933665 | 0.79 | CYP2A6 (0.48) | — | |
| SCHEMBL1249265 | 0.79 | CYP2A6 (0.48) | HSD11B1 | |
| SCHEMBL7461281 | 0.79 | CYP2A6 (0.48) | — | |
| SCHEMBL15459955 | 0.76 | HSD11B1 (0.53) | HSD11B1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605289-B2 | Benzamide derivatives and uses related thereto | AMGEN, INC. (US) | 2009-10-20 | — | — | US | disclosed |