SCHEMBL5402087

SCHEMBL5402087

C=Cc1ccc(C(C)(O)C(F)(F)F)cc1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 17/20 0.46
ALDH1A1 P00352 1/20 0.44
NR1H3 Q13133 2/20 0.41
NR1H2 P55055 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17445916 0.83 ALDH1A1 (0.48) ALDH1A1NR1H3NR1H2
SCHEMBL6838055 0.83 ALDH1A1 (0.48) HSD11B1ALDH1A1NR1H3NR1H2
SCHEMBL10165226 0.82 HSD11B1 (0.59) HSD11B1NR1H3NR1H2
SCHEMBL13675477 0.80 HSD11B1 (0.50) HSD11B1NR1H3
SCHEMBL12635205 0.80 HSD11B1 (0.35) HSD11B1NR1H3NR1H2
SCHEMBL3637391 0.80 HSD11B1 (0.50) HSD11B1NR1H3
SCHEMBL643498 0.79 NR1H2 (0.56) ALDH1A1NR1H3NR1H2
SCHEMBL1474017 0.79 ALDH1A1 (0.48) ALDH1A1NR1H3NR1H2
SCHEMBL15615108 0.79 ALDH1A1 (0.48) ALDH1A1NR1H3NR1H2
SCHEMBL14748502 0.79 PTPN5 (0.40) HSD11B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241441-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-12036025-B2 Bio-electrode, method for manufacturing bio-electrode, and method for measuring biological signal SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-16 US disclosed
US-12038692-B2 Method for producing substrate with patterned film and fluorine-containing copolymer CENTRAL GLASS COMPANY, LIMITED (JP) 2024-07-16 US disclosed
US-12038691-B2 Method for producing substrate with patterned film CENTRAL GLASS COMPANY, LIMITED (JP) 2024-07-16 US disclosed
US-20240215891-A1 Bio-Electrode Composition, Bio-Electrode, And Method For Manufacturing Bio-Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-04 US disclosed
US-20240215890-A1 Bio-Electrode, Bio-Electrode Composition, And Method For Manufacturing Bio-Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-04 US disclosed
US-20230400769-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2023-12-14 US disclosed
US-20230375925-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, COMPOUND, AND RESIN FUJIFILM CORPORATION (JP) 2023-11-23 US disclosed
US-11822248-B2 Coating compositions for use with an overcoated photoresist ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-11-21 US disclosed
US-20230367210-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2023-11-16 US disclosed
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110086312-A1 Positive-Working Photoimageable Bottom Antireflective Coating AZ ELECTRONIC MATERIALS USA CORP. 2011-04-14 US disclosed
WO-2011042770-A1 POSITIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA CORP. (US) 2011-04-14 WO disclosed
WO-2011039560-A1 POSITIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA CORP. (US) 2011-04-07 WO disclosed
US-20110076626-A1 Positive-Working Photoimageable Bottom Antireflective Coating MERCK PATENT GMBH (DE) 2011-03-31 US disclosed
US-7202011-B2 Photosensitive polymer including fluorine and resist composition containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-04-10 US disclosed
US-6800418-B2 ALLOWING DEVELOPMENT WITH CONVENTIONAL DEVELOPERS AND HAVING A HIGH TRANSMITTANCE AT A F2 EXCIMER LASER WAVELENGTH OF 157 NM, HYDROPHILICITY, ADHESION TO UNDERLAYER SAMSUNG ELECTRONICS (KR) 2004-10-05 US disclosed
US-20030228537-A1 Photosensitive polymer including fluorine and resist composition containing the same SAMSUNG ELECTRONICS CO.; LTD. (KR) 2003-12-11 US disclosed
US-20030157430-A1 Fluorine-containing photosensitive polymer having hydrate structure and resist composition comprising the same SAMSUNG ELECTRONICS CO., LTD. 2003-08-21 US disclosed
EP-0881266-A2 Polymers inhibiting denaturation of adsorbed proteins HÜLS AKTIENGESELLSCHAFT (DE) 1998-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF MLEC, NOD2, PAM HSD11B1 4670/4885ALDH1A1 3648/4885NR1H3 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.