Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ADH1B | P00325 | 1/20 | 0.47 |
| ▸ | ADH1C | P00326 | 1/20 | 0.47 |
| ▸ | ADH1A | P07327 | 1/20 | 0.47 |
| ▸ | ADH7 | P40394 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063684 | 1.00 | SIGMAR1 (0.61) | SIGMAR1KMT2AMEN1TAAR1BCHE | |
| SCHEMBL10696254 | 1.00 | SIGMAR1 (0.61) | SIGMAR1KMT2AMEN1TAAR1BCHE | |
| SCHEMBL28997722 | 0.83 | SIGMAR1 (0.63) | SIGMAR1KMT2AMEN1TAAR1BCHE | |
| SCHEMBL14637678 | 0.82 | SIGMAR1 (0.64) | SIGMAR1KMT2AMEN1TAAR1SMN1; SMN2 | |
| SCHEMBL27813235 | 0.81 | SIGMAR1 (0.61) | SIGMAR1KMT2AMEN1TAAR1BCHE | |
| SCHEMBL9063693 | 0.79 | SIGMAR1 (0.44) | SIGMAR1KMT2AMEN1TAAR1ADH1B | |
| SCHEMBL13675824 | 0.79 | SIGMAR1 (0.44) | SIGMAR1KMT2AMEN1TAAR1ADH1B | |
| SCHEMBL9878514 | 0.77 | SIGMAR1 (0.56) | SIGMAR1BCHESMN1; SMN2POLBALDH1A1 | |
| SCHEMBL17807875 | 0.77 | SIGMAR1 (0.56) | SIGMAR1KMT2AMEN1TAAR1BCHE | |
| SCHEMBL10134832 | 0.77 | SIGMAR1 (0.55) | SIGMAR1KMT2AMEN1TAAR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601842-B2 | Method for producing an optically active tetrahydroquinoline | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-13 | — | — | US | disclosed |