Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492284 | 0.81 | HTR2A (0.47) | SIGMAR1HTR2AMMP1MMP2MMP9 | |
| SCHEMBL28997722 | 0.79 | SIGMAR1 (0.63) | SIGMAR1SMN1; SMN2POLBCYP3A4BCHE | |
| SCHEMBL7103845 | 0.78 | CHRNB2 (0.68) | CHRNB2CHRNA4POLBCYP1A2ALDH1A1 | |
| SCHEMBL7103848 | 0.78 | CHRNB2 (0.68) | CHRNB2CHRNA4POLBCYP1A2ALDH1A1 | |
| SCHEMBL8825996 | 0.78 | HTR2A (0.51) | HTR2AMMP1MMP2MMP9RAB9A | |
| SCHEMBL8825991 | 0.78 | HTR2A (0.51) | HTR2AMMP1MMP2MMP9RAB9A | |
| SCHEMBL10696254 | 0.77 | SIGMAR1 (0.61) | SIGMAR1SMN1; SMN2POLBBCHEALDH1A1 | |
| SCHEMBL9063684 | 0.77 | SIGMAR1 (0.61) | SIGMAR1SMN1; SMN2POLBBCHEALDH1A1 | |
| SCHEMBL27813235 | 0.77 | SIGMAR1 (0.61) | SIGMAR1SMN1; SMN2POLBCYP3A4BCHE | |
| SCHEMBL13675822 | 0.77 | SIGMAR1 (0.61) | SIGMAR1SMN1; SMN2POLBBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017723-A | Psychotropic Agents | JOUVEINAL S.A. (FR) | 1991-05-21 | — | — | US | disclosed |
| EP-0361990-A1 | Disubstituted benzylamines, the process for their preparation, their use as drugs and their syntheses intermediates | JOUVEINAL S.A. (FR) | 1990-04-04 | — | — | EP | disclosed |