Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ACP3 | P15309 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954149 | 0.84 | SIGMAR1 (0.60) | SIGMAR1MEN1KMT2AACP3LMNA | |
| SCHEMBL8118291 | 0.77 | POLB (0.53) | SIGMAR1MEN1KMT2AACP3LMNA | |
| SCHEMBL172344 | 0.76 | SIGMAR1 (0.66) | SIGMAR1MEN1KMT2AACP3LMNA | |
| SCHEMBL13674818 | 0.73 | POLB (0.49) | SIGMAR1MEN1KMT2AACP3LMNA | |
| SCHEMBL28552790 | 0.72 | SIGMAR1 (0.55) | SIGMAR1MEN1KMT2AACP3LMNA | |
| SCHEMBL9768694 | 0.72 | SIGMAR1 (0.55) | SIGMAR1MEN1KMT2AACP3LMNA | |
| SCHEMBL28552787 | 0.72 | SIGMAR1 (0.55) | SIGMAR1MEN1KMT2AACP3LMNA | |
| SCHEMBL7673886 | 0.72 | SLC6A4 (0.35) | ALDH1A1SLC6A4 | |
| SCHEMBL13679348 | 0.71 | APAF1 (0.56) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL9063693 | 0.71 | SIGMAR1 (0.44) | SIGMAR1MEN1KMT2AACP3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601842-B2 | Method for producing an optically active tetrahydroquinoline | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-13 | — | — | US | disclosed |