SCHEMBL1367705

SCHEMBL1367705

[CH]c1ccc(C(C)(C)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.60
ESR2 Q92731 4/20 0.60
CYP3A4 P08684 2/20 0.60
ALDH1A1 P00352 2/20 0.60
NR3C2 P08235 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
AR P10275 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR6 P50406 1/20 0.44
ESRRG P62508 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MAPK1 P28482 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CNR1 P21554 3/20 0.41
CNR2 P34972 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535051 0.87 ESR1 (0.75) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL35881 0.84 ESR1 (0.70) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL14910456 0.84 ESR1 (0.70) ESR1ESR2CYP3A4ALDH1A1NR3C2
Water SCHEMBL27627259 0.81 ESR1 (0.67) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL8640106 0.79 ESR1 (0.65) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL6456244 0.79 ESR1 (0.65) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL18531361 0.79 ESR1 (0.65) ESR1ESR2CYP3A4ALDH1A1NR3C2
Methylamine SCHEMBL21647873 0.78 ESR1 (0.64) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL18913698 0.77 ESR1 (0.62) ESR1ESR2CYP3A4ALDH1A1NR3C2
SCHEMBL2299274 0.77 ESR1 (0.62) ESR1ESR2CYP3A4ALDH1A1NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3856654-B1 DUAL SPRAY PATTERN NOZZLES ICP CONSTRUCTION INC (US) 2024-04-24 EP disclosed
US-11850610-B2 Non-linear spray pattern nozzles ICP CONSTRUCTION, INC. (US) 2023-12-26 US disclosed
US-11738359-B2 Foam dispensing gun with third stream ICP CONSTRUCTION, INC. (US) 2023-08-29 US disclosed
US-11603484-B2 Process for seaming of artificial turf using low-pressure adhesives ICP CONSTRUCTION, INC. (US) 2023-03-14 US disclosed
US-11338991-B2 Fluid dispensing device ICP CONSTRUCTION, INC. (US) 2022-05-24 US disclosed
US-11224883-B2 Dual spray pattern nozzles ICP CONSTRUCTION, INC. (US) 2022-01-18 US disclosed
US-20210221602-A1 Fluid Dispensing Device ICP CONSTRUCTION, INC. (US) 2021-07-22 US disclosed
US-10934078-B2 Fluid dispensing device ICP CONSTRUCTION, INC. (US) 2021-03-02 US disclosed
US-20210023576-A1 Process for Seaming of Artificial Turf using Low-Pressure Adhesives ICP ADHESIVES AND SEALANTS, INC (US) 2021-01-28 US disclosed
US-20200261931-A1 Foam Dispensing Gun with Third Stream ICP ADHESIVES AND SEALANTS, INC. (US) 2020-08-20 US disclosed
WO-2008132616-A1 COLOR CHANGING CLEANSING COMPOSITION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-11-06 WO disclosed
US-20080234160-A1 Color changing cleansing composition KIMBERLY-CLARK WORLDWIDE, INC. 2008-09-25 US disclosed
EP-1960504-A1 COLOR CHANGING CLEANSING COMPOSITION Kimberly Clark Worldwide, Inc. (US) 2008-08-27 EP disclosed
WO-2008065553-A1 CLEANSING COMPOSITION INCORPORATING A BIOCIDE, HEATING AGENT AND THERMOCHROMIC SUBSTANCE KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-06-05 WO disclosed
US-20080132438-A1 Cleansing composition incorporating a biocide, heating agent and thermochromic substance KIMBERLY-CLARK WORLDWIDE, INC. 2008-06-05 US disclosed
WO-2007070118-A1 COLOR CHANGING CLEANSING COMPOSITION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2007-06-21 WO disclosed
US-20070142263-A1 Color changing cleansing composition KIMBERLY-CLARK WORLDWIDE, INC. 2007-06-21 US disclosed
US-4957949-A Thermochromic color masterbatch MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1990-09-18 US disclosed
US-4717710-A CHROMOGEN, TRIAZOLE, AZOMETHINE OR CARBOXYLIC ACID AMINE SALT, AND AN ALCOHOL, AMIDE OR ESTER SOLVENT MATSUI SHIKISO CHEMICAL CO. LTD. (JP) 1988-01-05 US disclosed
EP-0188635-A1 Thermochromic composition MATSUI SHIKISO CHEMICAL CO., LTD (JP) 1986-07-30 EP disclosed