Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15832876 | 0.97 | ALDH1A1 (0.58) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL6456244 | 0.97 | ESR1 (0.65) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL18801808 | 0.90 | KIF11 (0.53) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL7535051 | 0.89 | ESR1 (0.75) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL26411224 | 0.87 | NR3C2 (0.53) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL26410561 | 0.87 | CYP3A4 (0.50) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL26411228 | 0.87 | NR3C2 (0.53) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL26410671 | 0.87 | CYP3A4 (0.50) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL26410545 | 0.87 | CYP3A4 (0.50) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL16505951 | 0.86 | ESR1 (0.87) | ESR1ESR2ALDH1A1CYP3A4KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170153548-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-01 | — | — | US | disclosed |