Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18913698 | 0.97 | ESR1 (0.62) | ESR1ESR2CYP3A4ALDH1A1NR3C2 | |
| SCHEMBL15832876 | 0.94 | ALDH1A1 (0.58) | ESR1ESR2CYP3A4ALDH1A1NR3C2 | |
| SCHEMBL7535051 | 0.91 | ESR1 (0.75) | ESR1ESR2CYP3A4ALDH1A1NR3C2 | |
| SCHEMBL26411210 | 0.89 | CYP1A2 (0.58) | ESR1ESR2CYP3A4ALDH1A1NR3C2 | |
| SCHEMBL16505951 | 0.89 | ESR1 (0.87) | ESR1ESR2CYP3A4ALDH1A1NR3C2 | |
| SCHEMBL14910456 | 0.88 | ESR1 (0.70) | ESR1ESR2CYP3A4ALDH1A1NR3C2 | |
| SCHEMBL35881 | 0.88 | ESR1 (0.70) | ESR1ESR2CYP3A4ALDH1A1NR3C2 | |
| SCHEMBL18801808 | 0.87 | KIF11 (0.53) | ESR1ESR2CYP3A4ALDH1A1NR3C2 | |
| SCHEMBL16592828 | 0.87 | ESR1 (0.52) | ESR1ESR2CYP3A4ALDH1A1NR3C2 | |
| SCHEMBL13700827 | 0.87 | ESR1 (0.52) | ESR1ESR2CYP3A4ALDH1A1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919533-B1 | RADICAL-CURABLE SEAL MEMBER FOR FUEL CELL | SUMITOMO RIKO CO LTD (JP) | 2023-07-12 | — | — | EP | disclosed |
| US-20050159519-A1 | Phenylenediamine derivative, production method thereof and antioxidant for rubber using it as effective constituent | NOK CORPORATION | 2005-07-21 | — | — | US | disclosed |
| US-6329551-B1 | HIGH TEMPERATURE STABILITY | NOK CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6093853-A | N,N'-(MONO,DI, OR TRI-((ALKOXY)(SUBSTITUTED)PHENYLALKYL) PHENYL) PHENYLENEDIAMINE; MADE BY REACTING N,N'-DIPHENYL-1,4-PHENYLENEDIAMINE AND A STYRENE DERIVATIVE OF GIVEN FORMULA IN THE PRESENCE OF A PROTONIC ACID CATALYST | NOK CORPORATION (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0395183-B1 | Polyketone polymer compositions | SHELL INT RESEARCH (NL) | 1994-07-13 | — | — | EP | disclosed |
| US-4007230-A | A PHENOL AND 4,4'-BIS(ALPHA,ALPHA-DIMETHYLBENZYL)DIPHENYLAMINE | THE DOW CHEMICAL COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159519-A1 | Phenylenediamine derivative, production method thereof and antioxidant for rubber using it as effective constituent | PNMT, PRMT1, DNMT1 | ESR1 2335/4885ESR2 655/4885CYP3A4 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.