Prednisolone Phosphoric Acid

Prednisolone Phosphoric Acid

SCHEMBL136773

C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)COP(=O)(O)O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Prednisolone Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR3C1 known ✓ P04150 13/20 0.76
PGR P06401 4/20 0.78
HIF1A Q16665 3/20 0.78
HSD17B10 Q99714 2/20 0.76
CYP3A4 P08684 2/20 0.76
AR P10275 2/20 0.76
ABCB11 O95342 1/20 0.76
TNF P01375 1/20 0.76
IL6 P05231 1/20 0.76
SERPINA6 P08185 1/20 0.76
NR3C2 P08235 1/20 0.76
GLUL P15104 1/20 0.76
ADAM17 P78536 1/20 0.76
GPBAR1 Q8TDU6 1/20 0.76
CYP2C19 P33261 1/20 0.76
LMNA P02545 1/20 0.70
KMT2A Q03164 1/20 0.59
F2 P00734 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prednisolone Phosphoric Acid SCHEMBL21152848 1.00 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL21152533 1.00 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL26490459 1.00 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL13130881 1.00 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL20451347 1.00 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL7512 1.00 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL24622433 1.00 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Phosphoric Acid SCHEMBL5483617 0.99 PGR (0.77) PGRHIF1ANR3C1HSD17B10CYP3A4
SCHEMBL3634790 0.95 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
SCHEMBL20451346 0.95 PGR (0.81) PGRHIF1ANR3C1HSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4721214-A1 SYSTEM FOR CONTROLLING A CHARGE AND/OR DISCHARGE POWER OF AT LEAST ONE ENERGY STORE Enspired GmbH (AT) 2026-04-08 EP claimed
US-20250002591-A1 INHIBITOR OF TYPE 1 INTERFERON RECEPTOR STEROID SPARING IN SYSTEMIC LUPUS ERYTHERMATOSUS PATIENTS ASTRAZENECA AB (SE) 2025-01-02 US claimed
WO-2024251811-A1 SYSTEM FOR CONTROLLING A CHARGE AND/OR DISCHARGE POWER OF AT LEAST ONE ENERGY STORE enspired GmbH (AT) 2024-12-12 WO claimed
EP-4412641-A2 TREATMENT OF LUPUS Astrazeneca AB (SE) 2024-08-14 EP claimed
US-20240252446-A1 DERIVATIZED COLLAGEN-HYALURONIC ACID BASED IMPLANTS FOR SUSTAINED DELIVERY OF OPHTHALMIC DRUGS SUSTAINED DRUG DELIVERY LLC 2024-08-01 US claimed
EP-4377349-A1 TREATMENT OF LUPUS Astrazeneca AB (SE) 2024-06-05 EP claimed
US-20240176122-A1 DEVICES, SYSTEMS, AND METHODS FOR TREATING EAR DISORDERS SPIRAL THERAPEUTICS INC. 2024-05-30 US claimed
CN-118076379-A Treatment of lupus 阿斯利康(瑞典)有限公司 2024-05-24 CN claimed
EP-4337696-A1 INHIBITOR OF TYPE 1 INTERFERON RECEPTOR STEROID SPARING IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS Astrazeneca AB (SE) 2024-03-20 EP claimed
CN-117677638-A Treatment of lupus 阿斯利康(瑞典)有限公司 2024-03-08 CN claimed
EP-0036138-B2 Composition of matter for topical application comprising a bio-affecting agent and N,N-diethyl-m-toluamide MERCK & CO. INC. (US) 1989-10-25 EP claimed
EP-0069385-B1 USE OF EUCALYPTOL FOR ENHANCING SKIN PERMEATION OF BIOAFFECTING AGENTS MERCK & CO. INC. (US) 1987-10-14 EP claimed
EP-0036138-B1 COMPOSITION OF MATTER FOR TOPICAL APPLICATION COMPRISING A BIO-AFFECTING AGENT AND N,N-DIETHYL-M-TOLUAMIDE MERCK & CO. INC. (US) 1985-08-28 EP claimed
EP-0147780-A2 Drug delivery device MERCK & CO. INC. (US) 1985-07-10 EP claimed
US-4407792-A HIGH MOLECULAR WEIGHT ETHYLENE-MALEIC ANHYDRIDE COPOLYMER ALCON LABORATORIES, INC. (US) 1983-10-04 US claimed
EP-0069385-A2 Use of eucalyptol for enhancing skin permeation of bioaffecting agents MERCK & CO. INC. (US) 1983-01-12 EP claimed
EP-0036138-A2 Composition of matter for topical application comprising a bio-affecting agent and N,N-diethyl-m-toluamide MERCK & CO. INC. (US) 1981-09-23 EP claimed
US-4271143-A ACRYLIC POLYMER GEL ALCON LABORATORIES, INC. (US) 1981-06-02 US claimed
US-4014335-A Ocular drug delivery device ALZA CORPORATION (US) 1977-03-29 US claimed
US-4001388-A POLYESTERS ALZA CORPORATION (US) 1977-01-04 US claimed