Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 13/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.78 |
| ▸ | AR | P10275 | 2/20 | 0.78 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.78 |
| ▸ | TNF | P01375 | 1/20 | 0.78 |
| ▸ | IL6 | P05231 | 1/20 | 0.78 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.78 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.78 |
| ▸ | GLUL | P15104 | 1/20 | 0.78 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.78 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prednisolone Phosphoric Acid SCHEMBL26490459 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Phosphoric Acid SCHEMBL13130881 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| SCHEMBL3634790 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Phosphoric Acid SCHEMBL7512 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Phosphoric Acid SCHEMBL20451347 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Phosphoric Acid SCHEMBL24622433 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Phosphoric Acid SCHEMBL136773 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Phosphoric Acid SCHEMBL21152533 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Phosphoric Acid SCHEMBL21152848 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Phosphoric Acid SCHEMBL23563 | 0.94 | PGR (0.77) | PGRHIF1ANR3C1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180221406-A1 | THERAPEUTIC COMBINATIONS OF ANTIVIRAL AND ANTI-INFLAMMATORY THERAPIES | FORESIGHT BIOTHERAPEUTICS, INC. (US) | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221406-A1 | THERAPEUTIC COMBINATIONS OF ANTIVIRAL AND ANTI-INFLAMMATORY THERAPIES | EIF2AK2, IRF3, IFNG | PGR 733/4885HIF1A 514/4885NR3C1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.