Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273202 | 0.82 | OAT (0.42) | CYP19A1LMNACHRM1POLBCYP3A4 | |
| SCHEMBL399295 | 0.81 | CYP19A1 (0.37) | CYP19A1LMNACHRM1POLBCA12 | |
| SCHEMBL13677475 | 0.76 | CYP19A1 (0.40) | CYP19A1CHRM3LMNACHRM1CHRM2 | |
| SCHEMBL4266335 | 0.76 | CYP19A1 (0.40) | CYP19A1CHRM3LMNACHRM1CHRM2 | |
| SCHEMBL2585385 | 0.76 | CYP19A1 (0.40) | CYP19A1CHRM3LMNACHRM1CHRM2 | |
| SCHEMBL6538254 | 0.74 | CHRM3 (0.38) | CHRM3LMNACHRM1CHRM2CHRM4 | |
| SCHEMBL4593737 | 0.74 | CHRM3 (0.38) | CHRM3LMNACHRM1CHRM2CHRM4 | |
| SCHEMBL13677468 | 0.74 | CHRM3 (0.38) | CHRM3LMNACHRM1CHRM2CHRM4 | |
| SCHEMBL31294258 | 0.73 | RAB9A (0.34) | CYP19A1LMNAHSD17B10GAAADORA3 | |
| SCHEMBL19944587 | 0.73 | CHRM3 (0.37) | CHRM3LMNACHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247770-A1 | PROCESS FOR MAKING LACTAM TACHYKININ RECEPTOR ANTAGONISTS | MSD K.K. (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090247770-A1 | PROCESS FOR MAKING LACTAM TACHYKININ RECEPTOR ANTAGONISTS | MSD K.K. (JP) | 2009-10-01 | — | — | US | disclosed |
| WO-2008021029-A2 | PROCESS FOR MAKING LACTAM TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247770-A1 | PROCESS FOR MAKING LACTAM TACHYKININ RECEPTOR ANTAGONISTS | TACR1, TACR2, NPSR1 | CYP19A1 798/4885CHRM3 1820/4885LMNA 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.