Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246016 | 0.91 | MAPK9 (0.48) | MAPK9MAPK14 | |
| SCHEMBL3252013 | 0.90 | MAPK9 (0.46) | MAPK9MAPK14 | |
| SCHEMBL3257573 | 0.87 | MAPK9 (0.53) | MAPK9MAPK14 | |
| SCHEMBL3253064 | 0.86 | MAPK14 (0.46) | MAPK9MAPK14 | |
| SCHEMBL3249327 | 0.86 | MAPK9 (0.51) | MAPK9MAPK14 | |
| SCHEMBL3251945 | 0.85 | MAPK14 (0.45) | MAPK9MAPK14 | |
| SCHEMBL3254571 | 0.85 | MAPK14 (0.53) | MAPK9MAPK14 | |
| SCHEMBL3251993 | 0.83 | MAPK14 (0.47) | MAPK9MAPK14 | |
| SCHEMBL13678720 | 0.83 | MAPK9 (0.56) | MAPK9MAPK14 | |
| SCHEMBL3246009 | 0.83 | MAPK9 (0.48) | MAPK9MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258874-A1 | PYRAZOLO-HETEROARYL COMPOUNDS | NOVARTIS AG (CH) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258874-A1 | PYRAZOLO-HETEROARYL COMPOUNDS | IL1R1, IL1A, IL1B | MAPK9 2483/4885MAPK14 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.