SCHEMBL13679136

SCHEMBL13679136

NC(=O)c1cc2c3c(cccc3c1)-c1nc3cc(S(=O)(=O)O)ccc3nc1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
RAB9A P51151 3/20 0.38
MEN1 O00255 2/20 0.38
HTT P42858 2/20 0.38
KMT2A Q03164 2/20 0.38
PKM P14618 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 4/20 0.33
MAPT P10636 3/20 0.33
KDM4E B2RXH2 3/20 0.33
HPGD P15428 3/20 0.33
GAA P10253 3/20 0.33
HSD17B10 Q99714 2/20 0.33
POLB P06746 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13366658 0.92 TDP1 (0.39) CYP1A2RAB9AMEN1HTTKMT2A
SCHEMBL842805 0.88 NT5E (0.37) CYP1A2RAB9AMEN1HTTKMT2A
SCHEMBL824403 0.86 RAB9A (0.43) CYP1A2RAB9AMEN1HTTKMT2A
SCHEMBL13366657 0.85 TDP1 (0.42) CYP1A2RAB9AMEN1HTTKMT2A
SCHEMBL3222486 0.85 CYP1A2 (0.57) CYP1A2RAB9AMEN1HTTKMT2A
SCHEMBL14845574 0.83 TDP1 (0.48) CYP1A2RAB9AMEN1HTTKMT2A
SCHEMBL840932 0.81 TDP1 (0.51) CYP1A2RAB9AMEN1HTTKMT2A
SCHEMBL14336337 0.81 APEX1 (0.38) CYP1A2RAB9AMEN1HTTKMT2A
SCHEMBL13679139 0.79 CHEK2 (0.32) MEN1HTTKMT2ATDP1ALDH1A1
SCHEMBL2396254 0.78 MEN1 (0.56) CYP1A2RAB9AMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8416376-B2 Compensated in-plane switching mode liquid crystal display CRYSOPTIX KK (JP) 2013-04-09 US disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed