SCHEMBL824403

SCHEMBL824403

NC(=O)c1ccc2nc3c(nc2c1)-c1cccc2cc(S(=O)(=O)O)cc-3c12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
CYP1A2 P05177 1/20 0.41
HPGD P15428 6/20 0.37
ALDH1A1 P00352 5/20 0.37
GAA P10253 3/20 0.36
KDM4E B2RXH2 2/20 0.36
NPC1 O15118 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
NAMPT P43490 2/20 0.35
CHEK2 O96017 4/20 0.34
CLTC Q00610 1/20 0.34
CSNK2A2 P19784 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2396254 0.89 MEN1 (0.56) RAB9AMEN1KMT2APKMHTT
SCHEMBL2395393 0.89 MEN1 (0.56) RAB9AMEN1KMT2APKMHTT
Ammonia Solution, Strong SCHEMBL2396268 0.88 MEN1 (0.55) RAB9AMEN1KMT2APKMHTT
Ammonia Solution, Strong SCHEMBL2395604 0.88 MEN1 (0.55) RAB9AMEN1KMT2APKMHTT
Ammonia Solution, Strong SCHEMBL2395606 0.88 MEN1 (0.55) RAB9AMEN1KMT2APKMHTT
Ammonia Solution, Strong SCHEMBL2396272 0.88 MEN1 (0.55) RAB9AMEN1KMT2APKMHTT
SCHEMBL13679136 0.86 CYP1A2 (0.43) RAB9AMEN1KMT2APKMHTT
SCHEMBL1450590 0.84 RAB9A (0.44) RAB9AMEN1KMT2APKMHTT
SCHEMBL840932 0.83 TDP1 (0.51) RAB9AMEN1KMT2APKMHTT
SCHEMBL17742670 0.82 CYP1A2 (0.42) RAB9AMEN1KMT2APKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8416376-B2 Compensated in-plane switching mode liquid crystal display CRYSOPTIX KK (JP) 2013-04-09 US disclosed
US-8416376-B2 Compensated in-plane switching mode liquid crystal display CRYSOPTIX KK (JP) 2013-04-09 US disclosed
US-8142863-B2 Color liquid crystal display and compensation panel Crysoptix, KK (JP) 2012-03-27 US disclosed
US-8142863-B2 Color liquid crystal display and compensation panel Crysoptix, KK (JP) 2012-03-27 US disclosed
US-7889297-B2 Liquid crystal display operating in a vertically aligned mode Crysoptix, KK (JP) 2011-02-15 US disclosed
US-7889297-B2 Liquid crystal display operating in a vertically aligned mode Crysoptix, KK (JP) 2011-02-15 US disclosed
US-20100149471-A1 Compensated In-Plane Switching Mode Liquid Crystal Display CRYSOPTIX KK (JP) 2010-06-17 US disclosed
US-20100149471-A1 Compensated In-Plane Switching Mode Liquid Crystal Display CRYSOPTIX KK (JP) 2010-06-17 US disclosed
US-20100118241-A1 Liquid Crystal Display Operating in a Vertically Aligned Mode CRYSOPTIX KK (JP) 2010-05-13 US disclosed
US-20100118241-A1 Liquid Crystal Display Operating in a Vertically Aligned Mode CRYSOPTIX KK (JP) 2010-05-13 US disclosed
WO-2009130676-A2 COLOR LIQUID CRYSTAL DISPLAY AND COMPENSATION PANEL CRYSOPTIX KK (JP) 2009-10-29 WO disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
US-20090161037-A1 Backlight Module and Liquid Crystal Display Incorporating the Same CRYSOPTIX KK (JP) 2009-06-25 US disclosed
US-20090161037-A1 Backlight Module and Liquid Crystal Display Incorporating the Same CRYSOPTIX KK (JP) 2009-06-25 US disclosed