Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28677838 | 0.87 | LMNA (0.55) | LMNAALDH1A1TDP1BLMPTPN1 | |
| SCHEMBL23710711 | 0.85 | ALDH1A1 (0.64) | LMNAALDH1A1TDP1MEN1CYP3A4 | |
| SCHEMBL6903881 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4 | |
| SCHEMBL23772032 | 0.85 | ALDH1A1 (0.64) | LMNAALDH1A1TDP1MEN1CYP3A4 | |
| SCHEMBL1703329 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TDP1 | |
| SCHEMBL22653567 | 0.83 | ALDH1A1 (0.45) | LMNAALDH1A1TDP1BLMCYP3A4 | |
| SCHEMBL23696604 | 0.83 | ALDH1A1 (0.56) | LMNAALDH1A1TDP1CYP3A4CACNA2D1 | |
| SCHEMBL14564100 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL20124078 | 0.82 | ALDH1A1 (0.65) | LMNAALDH1A1TDP1BLMCYP3A4 | |
| SCHEMBL3972494 | 0.80 | LMNA (0.52) | LMNAALDH1A1TDP1BLMPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192125-B9 | MONO-SUBSTITUTED 3-PROPYL GAMMA-AMINOBUTYRIC ACIDS | WARNER LAMBERT CO (US) | 2009-09-16 | — | — | EP | disclosed |
| EP-1192125-B1 | MONO-SUBSTITUTED 3-PROPYL GAMMA-AMINOBUTYRIC ACIDS | WARNER LAMBERT CO (US) | 2008-12-31 | — | — | EP | disclosed |