Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442601 | 0.88 | ABCB1 (0.68) | ABCB1MEN1KMT2AMAPTNOX1 | |
| SCHEMBL717762 | 0.82 | ABCB1 (0.68) | ABCB1MAPTNOX1 | |
| SCHEMBL13679681 | 0.78 | ABCB1 (0.43) | ABCB1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6625154 | 0.78 | ABCB1 (0.69) | ABCB1MAPTNOX1 | |
| SCHEMBL3828912 | 0.73 | ABCB1 (0.69) | ABCB1MAPTNOX1 | |
| SCHEMBL13679656 | 0.73 | ABCB1 (0.70) | ABCB1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13679689 | 0.70 | ABCB1 (0.73) | ABCB1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13679704 | 0.70 | ABCB1 (0.42) | ABCB1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL3824112 | 0.70 | ABCB1 (0.60) | ABCB1ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL13780563 | 0.70 | ABCB1 (0.91) | ABCB1MAPTNOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999835-B1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | TAIJI BIOMEDICAL INC (US) | 2009-09-09 | — | — | EP | disclosed |