Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14058913 | 0.86 | MAPT (0.43) | LMNASCN5ACYP1A2HRH2MAPK1 | |
| SCHEMBL22082127 | 0.79 | ABL1 (0.51) | ALDH1A1ABL1 | |
| SCHEMBL28802324 | 0.79 | ABL1 (0.51) | ALDH1A1ABL1 | |
| SCHEMBL27861311 | 0.79 | ABL1 (0.51) | ALDH1A1ABL1 | |
| SCHEMBL18627182 | 0.77 | LMNA (0.51) | LMNASCN5ACYP1A2HRH2MAPK1 | |
| SCHEMBL2493444 | 0.77 | LMNA (0.42) | LMNASCN5ACYP1A2HRH2MAPK1 | |
| SCHEMBL181559 | 0.76 | MAPT (0.52) | LMNASCN5ACYP1A2HRH2MAPK1 | |
| SCHEMBL854855 | 0.75 | EPHX1 (0.51) | LMNASCN5ACYP1A2HRH2MAPK1 | |
| SCHEMBL8772822 | 0.74 | MAPT (0.46) | ALDH1A1HIF1AGAA | |
| SCHEMBL11476807 | 0.73 | EPHX1 (0.50) | LMNASCN5ACYP1A2HRH2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999835-B1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | TAIJI BIOMEDICAL INC (US) | 2009-09-09 | — | — | EP | disclosed |
| EP-2082740-A2 | Use of imidazole derivatives as MDR modulators | Taiji Biomedical, Inc. (US) | 2009-07-29 | — | — | EP | disclosed |