Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28802324 | 0.92 | ABL1 (0.51) | MAPTALDH1A1ABL1KCNH3PRSS1 | |
| SCHEMBL22082127 | 0.92 | ABL1 (0.51) | MAPTALDH1A1ABL1KCNH3PRSS1 | |
| SCHEMBL27861311 | 0.92 | ABL1 (0.51) | MAPTALDH1A1ABL1KCNH3PRSS1 | |
| SCHEMBL181559 | 0.89 | MAPT (0.52) | MAPTLMNASCN5AALDH1A1CYP1A2 | |
| SCHEMBL8772822 | 0.86 | MAPT (0.46) | MAPTALDH1A1GAAARCA1 | |
| SCHEMBL13679674 | 0.86 | LMNA (0.39) | LMNASCN5AALDH1A1CYP1A2MAOA | |
| SCHEMBL18627182 | 0.86 | LMNA (0.51) | LMNASCN5AALDH1A1CYP1A2MAOA | |
| SCHEMBL30800856 | 0.82 | MAPT (0.46) | MAPTLMNASCN5AALDH1A1CYP1A2 | |
| SCHEMBL1241959 | 0.81 | ABL1 (0.56) | MAPTLMNASCN5AALDH1A1CYP1A2 | |
| SCHEMBL11528091 | 0.81 | MAPT (0.55) | MAPTALDH1A1CYP1A2SIGMAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906808-B | One kind contains tertiary butyl and polynary aryl oxide structure soluble polyimide and preparation method thereof | 上海交通大学 | 2018-07-03 | — | — | CN | claimed |
| CN-101531598-A | Tert-butyl benzidine and preparation method thereof | UNIV EAST CHINA SCIENCE & TECH | 2009-09-16 | — | — | CN | claimed |
| CN-112175171-B | Novel donor-acceptor polymer functionalized photoacoustic developer and preparation method thereof | 苏州希夫安材料科技有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-112175171-A | Novel donor-acceptor polymer functionalized photoacoustic developer and preparation method thereof | 南京优写智能科技有限公司 | 2021-01-05 | — | — | CN | disclosed |
| US-10370484-B2 | Polymer compound and light emitting device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-08-06 | — | — | US | disclosed |
| CN-105906808-B | One kind contains tertiary butyl and polynary aryl oxide structure soluble polyimide and preparation method thereof | 上海交通大学 | 2018-07-03 | — | — | CN | disclosed |
| US-9346795-B2 | Substituted sulfonamides useful as antiapoptotic Bcl inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| CN-105542163-A | Soluble polyimide with tert-butyl, ether bond, and bisphenol A structure and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2016-05-04 | — | — | CN | disclosed |
| CN-102448920-B | Antiviral compounds and uses thereof | ABBVIE (US) | 2016-04-06 | — | — | CN | disclosed |
| CN-103732589-B | Can be used as the sulphonamide of the replacement of anti-apoptotic BCL inhibitor | BRISTOL-MYERS SQUIBB CO. (US) | 2016-03-30 | — | — | CN | disclosed |
| EP-2714681-B1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-06-24 | — | — | EP | disclosed |
| CN-103910882-A | High-Tg soluble polyimide and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2014-07-09 | — | — | CN | disclosed |
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| WO-2012162365-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-29 | — | — | WO | disclosed |
| CN-102448920-A | Antiviral compounds and uses thereof | ABBOTT LAB | 2012-05-09 | — | — | CN | disclosed |
| CN-101531598-A | Tert-butyl benzidine and preparation method thereof | UNIV EAST CHINA SCIENCE & TECH | 2009-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BCL2, BAX, BCL2A1 | MAPT 4608/4885LMNA 2227/4885SCN5A 1058/4885 |
| US-10370484-B2 | Polymer compound and light emitting device using the same | ARL1, NMRAL1, RB1 | MAPT 3248/4885LMNA 3572/4885SCN5A 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.