Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 5/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367965 | 1.00 | POLB (0.39) | POLBS1PR3SMN1; SMN2LMNAMAPT | |
| SCHEMBL1366146 | 0.96 | POLB (0.42) | POLBS1PR3SMN1; SMN2LMNAMAPT | |
| SCHEMBL1366149 | 0.96 | POLB (0.42) | POLBS1PR3SMN1; SMN2LMNAMAPT | |
| SCHEMBL1365874 | 0.90 | AR (0.37) | S1PR3SMN1; SMN2ARPGRALDH1A1 | |
| SCHEMBL1365875 | 0.90 | AR (0.37) | S1PR3SMN1; SMN2ARPGRALDH1A1 | |
| SCHEMBL223992 | 0.89 | AR (0.45) | S1PR3ARPGRALDH1A1 | |
| SCHEMBL223991 | 0.89 | AR (0.45) | S1PR3ARPGRALDH1A1 | |
| SCHEMBL223682 | 0.88 | AR (0.38) | S1PR3SMN1; SMN2S1PR1ARPGR | |
| SCHEMBL223681 | 0.88 | AR (0.38) | S1PR3SMN1; SMN2S1PR1ARPGR | |
| SCHEMBL222985 | 0.85 | AR (0.45) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067448-B2 | Selective androgen receptor modulators | RADIUS HEALTH, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110224267-A1 | Selective androgen receptor modulators | Radius Health,Inc. (US) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224267-A1 | Selective androgen receptor modulators | AR, SHBG, GPR119 | POLB 3458/4885S1PR3 2534/4885SMN1; SMN2 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.