SCHEMBL13680268

SCHEMBL13680268

N#CC(C#N)=C1C=C(/C=C/c2ccc(N(c3ccccc3)c3ccccc3)cc2)OC(c2ccccc2)=C1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.31
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
RELA Q04206 1/20 0.31
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7999749 0.90 RELA (0.35) APPMAPTRELAHDAC6
SCHEMBL10104129 0.90 RELA (0.35) APPMAPTRELAHDAC6
SCHEMBL7999745 0.90 RELA (0.35) APPMAPTRELAHDAC6
SCHEMBL13680267 0.90 RELA (0.35) APPMAPTRELAHDAC6
SCHEMBL5448209 0.85 RELA (0.34) APPMAPTSMN1; SMN2RELAHDAC6
SCHEMBL5448210 0.85 RELA (0.34) APPMAPTSMN1; SMN2RELAHDAC6
SCHEMBL14224319 0.85 RELA (0.47) APPMAPTRELA
SCHEMBL8025506 0.83 HDAC6 (0.33) MAPTHDAC6
SCHEMBL15102163 0.83 MAPT (0.33) APPMAPT
SCHEMBL8025502 0.83 HDAC6 (0.33) MAPTHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9691999-B2 Photoelectric conversion device vapor deposition material, photoelectric conversion device, sensor, and imaging device FUJIFILM CORPORATION (JP) 2017-06-27 US disclosed
US-9012761-B2 Organic photoelectric conversion material and photoelectric conversion element using the same FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-8822808-B2 Photoelectric conversion device, method for manufacturing the same, photo sensor and imaging device FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-20140138522-A1 PHOTOELECTRIC CONVERSION DEVICE VAPOR DEPOSITION MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, SENSOR, AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2014-05-22 US disclosed
US-20130015547-A1 PHOTOELECTRIC CONVERSION DEVICE, METHOD FOR MANUFACTURING THE SAME, PHOTO SENSOR AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-17 US disclosed
US-20090229670-A1 ORGANIC PHOTOELECTRIC CONVERSION MATERIAL AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090229670-A1 ORGANIC PHOTOELECTRIC CONVERSION MATERIAL AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME TRRAP, RARA, RARG APP 4017/4885MAPT 3828/4885SMN1; SMN2 4294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.