Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12898270 | 0.92 | TDP1 (0.50) | TDP1LMNAMEN1KMT2ASIRT6 | |
| SCHEMBL32659719 | 0.92 | PDGFRB (0.51) | TDP1LMNAMEN1KMT2ASIRT6 | |
| SCHEMBL3898466 | 0.92 | TDP1 (0.54) | TDP1LMNAMEN1KMT2ASIRT6 | |
| SCHEMBL2903296 | 0.90 | TDP1 (0.53) | TDP1LMNAMEN1KMT2ASIRT6 | |
| SCHEMBL14993469 | 0.89 | PDGFRB (0.59) | TDP1LMNAMEN1KMT2ASIRT6 | |
| SCHEMBL2798716 | 0.87 | ALDH1A1 (0.53) | TDP1LMNAMEN1KMT2ASIRT6 | |
| SCHEMBL1786813 | 0.87 | MEN1 (0.51) | TDP1LMNAMEN1KMT2ASIRT6 | |
| SCHEMBL20872770 | 0.86 | TDP1 (0.47) | TDP1LMNAMEN1KMT2ASIRT6 | |
| SCHEMBL3998487 | 0.86 | ALDH1A1 (0.51) | TDP1LMNAMEN1KMT2APDGFRB | |
| SCHEMBL194902 | 0.86 | TDP1 (0.50) | TDP1LMNAMEN1KMT2ASIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582770-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-01 | — | — | US | disclosed |