Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404645 | 0.81 | HSD17B1 (0.55) | ACHEMAP4K4RAB9AENPP3IDO1 | |
| SCHEMBL2757248 | 0.81 | MAP4K4 (0.46) | ACHEMAP4K4RAB9AENPP3IDO1 | |
| SCHEMBL12947816 | 0.78 | CYP2A6 (0.52) | ACHECYP11B2CYP2A6CYP2B6CYP3A4 | |
| SCHEMBL30098552 | 0.78 | MAP4K4 (0.68) | CYP11B2CYP2A6CYP2B6CYP3A4CYP2E1 | |
| SCHEMBL21410258 | 0.78 | CYP11B2 (0.45) | GRIN1GRIN2BCYP11B2CYP2A6CYP2B6 | |
| SCHEMBL20098737 | 0.78 | MAP4K4 (0.44) | GRIN1GRIN2BACHEMAP4K4RAB9A | |
| SCHEMBL4406991 | 0.78 | HSD17B1 (0.51) | ACHEMAP4K4RAB9AENPP3IDO1 | |
| SCHEMBL12349144 | 0.78 | MAP4K4 (0.68) | MAP4K4RAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL11158811 | 0.78 | CYP2A6 (0.55) | CYP2A6MAP4K4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL32663642 | 0.78 | CYP2A6 (0.55) | CYP2A6MAP4K4RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |