Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13750509 | 0.81 | PTGS2 (0.47) | TRPV3CYP2A6PTGS2TGFBR1 | |
| SCHEMBL17609694 | 0.81 | TRPV3 (0.51) | TRPV3KCNH2SCN9A | |
| SCHEMBL15935412 | 0.80 | CCR1 (0.50) | TRPV3CYP2A6PTGS2CCR1CCR8 | |
| SCHEMBL3421947 | 0.79 | CYP2A6 (0.65) | CYP2A6CCR1CCR8TGFBR1 | |
| SCHEMBL30146674 | 0.79 | CYP2A6 (0.65) | CYP2A6CCR1CCR8TGFBR1 | |
| SCHEMBL12538766 | 0.78 | KCNH2 (0.43) | TRPV3PTGS2KCNH2 | |
| SCHEMBL12538603 | 0.78 | TRPV3 (0.46) | TRPV3KCNH2SCN9A | |
| SCHEMBL13680479 | 0.78 | CYP2A6 (0.54) | CYP2A6CCR1CCR8TGFBR1 | |
| SCHEMBL28864065 | 0.77 | KDM4E (0.46) | TRPV3KCNH2 | |
| SCHEMBL12538145 | 0.77 | TRPV3 (0.54) | TRPV3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715430-B | inhibition of transient receptor potential A1 ion channels | 伊莱利利公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-106715430-A | Inhibition of transient receptor potential A1 ion channels | 海德拉生物科学公司 | 2017-05-24 | — | — | CN | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |