Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23197679 | 0.79 | TDP1 (0.56) | ALDH1A1TSHRKDM4ENPC1LMNA | |
| SCHEMBL17778297 | 0.79 | NQO2 (0.47) | ALDH1A1TSHRCYP2C19KDM4ENPC1 | |
| SCHEMBL13680605 | 0.77 | HRH3 (0.50) | HRH3TAAR1ALDH1A1TSHRCYP2A6 | |
| SCHEMBL13680604 | 0.77 | GSK3B (0.42) | ALDH1A1TSHRCYP2C19KDM4ENPC1 | |
| SCHEMBL12679031 | 0.75 | HRH3 (1.00) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL13680606 | 0.74 | GSK3B (0.38) | ALDH1A1TSHRKDM4ENPC1LMNA | |
| SCHEMBL20782264 | 0.74 | ESR1 (0.44) | ALDH1A1TSHRKDM4ENPC1LMNA | |
| SCHEMBL2319851 | 0.73 | TDP1 (0.48) | ALDH1A1TSHRACHECYP2C19KDM4E | |
| SCHEMBL659509 | 0.72 | HRH3 (0.82) | HRH3TAAR1ALDH1A1TSHRHDAC6 | |
| SCHEMBL13680980 | 0.72 | HRH3 (0.44) | HRH3TAAR1ALDH1A1TSHRHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |