Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | CDC25C | P30307 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.50 |
| ▸ | CACNG8 | Q8WXS5 | 5/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680627 | 0.81 | CA12 (0.51) | CDC25ACDC25BCDC25CDUSP3PDE3B | |
| SCHEMBL13680622 | 0.79 | PDE3B (0.56) | CDC25ACDC25BCDC25CDUSP3PDE3B | |
| SCHEMBL13680624 | 0.77 | NPC1 (0.51) | TLR9TLR8TLR7CYP2E1CYP3A4 | |
| SCHEMBL19626747 | 0.77 | CDC25A (0.58) | CDC25ACDC25BCDC25CDUSP3PDE3B | |
| SCHEMBL6200129 | 0.76 | CDC25A (0.64) | CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL13680995 | 0.76 | CDC25A (0.48) | CDC25ACDC25BCDC25CDUSP3PDE3B | |
| SCHEMBL8198560 | 0.75 | CYP3A4 (0.60) | TLR9TLR8TLR7GABRA1GABRG2 | |
| SCHEMBL13680616 | 0.75 | EGFR (0.51) | TLR9TLR8TLR7CYP2E1CYP3A4 | |
| SCHEMBL13680617 | 0.74 | GSK3B (0.61) | TLR9TLR8TLR7CYP2E1CYP3A4 | |
| SCHEMBL19625362 | 0.74 | CDC25A (0.55) | CDC25ACDC25BCDC25CDUSP3PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |