Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.64 |
| ▸ | PARP11 | Q9NR21 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424565 | 0.90 | PARP10 (0.61) | PARP10PARP11CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL19100757 | 0.86 | HSD17B1 (0.62) | PARP10PARP11CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL1747435 | 0.84 | HSD17B1 (0.69) | PARP10PARP11CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL28655414 | 0.84 | HSD17B1 (0.78) | PARP10PARP11CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL1745161 | 0.82 | HSD17B1 (0.71) | PARP10PARP11CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL3630871 | 0.80 | HSD17B1 (0.54) | PARP10PARP11CYP1A2CYP11B1CYP11B2 | |
| Dimethylamine SCHEMBL3994802 | 0.80 | HSD17B1 (0.63) | PARP10PARP11CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL3989386 | 0.80 | CASP1 (0.66) | PARP10PARP11CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL6192593 | 0.80 | PARP10 (0.64) | PARP10PARP11CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL29726014 | 0.80 | CASP1 (0.59) | PARP10PARP11CYP1A2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |