Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 2/20 | 0.63 |
| ▸ | HPGDS | O60760 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128364 | 0.91 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL22377002 | 0.89 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13680651 | 0.82 | IDO1 (0.47) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL16727393 | 0.82 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL10128400 | 0.81 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL22377049 | 0.81 | KMO (0.49) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL11933090 | 0.80 | NPC1 (0.75) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13910154 | 0.80 | NPC1 (0.75) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL13910156 | 0.80 | NPC1 (0.75) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL10091193 | 0.80 | NPC1 (0.75) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |