Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | CCR8 | P51685 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 10/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680679 | 0.82 | CCR1 (0.60) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL23243808 | 0.82 | SCN9A (0.37) | CCR1CCR8CYP2A6SCN9AMEN1 | |
| SCHEMBL13680673 | 0.79 | CCR1 (0.56) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL13681326 | 0.79 | CCR1 (0.50) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL16068071 | 0.78 | SCN9A (0.45) | TGFBR1SCN9A | |
| SCHEMBL30146674 | 0.77 | CYP2A6 (0.65) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL3421947 | 0.77 | CYP2A6 (0.65) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL13680586 | 0.76 | CCR1 (0.52) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL13680674 | 0.76 | CCR1 (0.52) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL13680680 | 0.76 | CYP2A6 (0.54) | CCR1CCR8CYP2A6METAP2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |