Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680679 | 0.81 | CCR1 (0.60) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL23243800 | 0.81 | TRPV3 (0.40) | CYP2A6GRM5KCNH2SCN9ATRPV3 | |
| SCHEMBL13680549 | 0.79 | CYP2A6 (0.51) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL13680673 | 0.78 | CCR1 (0.56) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL13680677 | 0.76 | CCR1 (0.54) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL30146674 | 0.76 | CYP2A6 (0.65) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL3421947 | 0.76 | CYP2A6 (0.65) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL13680586 | 0.75 | CCR1 (0.52) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL13680680 | 0.75 | CYP2A6 (0.54) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL13680675 | 0.75 | CCR1 (0.52) | CCR1CCR8CYP2A6METAP2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |