Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681011 | 0.78 | ALDH1A1 (0.35) | ALDH1A1POLBKDM4EKMT2AMAPT | |
| SCHEMBL14220727 | 0.72 | KDM4E (0.46) | ALDH1A1RAB9AKDM4EMAPTTDP1 | |
| SCHEMBL13680646 | 0.71 | EIF2AK2 (0.46) | ALPIALPGPLAA | |
| SCHEMBL6938232 | 0.71 | ALPI (0.54) | ALDH1A1POLBRAB9AKMT2AMAPT | |
| SCHEMBL13680671 | 0.70 | CYP2A6 (0.44) | ALDH1A1KDM4EMAPTBTKHTT | |
| SCHEMBL16437819 | 0.69 | CREBBP (0.49) | RAB9AL3MBTL1BTKNPC1CCNC | |
| SCHEMBL13680736 | 0.68 | BTK (0.39) | ALDH1A1RAB9AKDM4EUSP2BTK | |
| SCHEMBL22448097 | 0.67 | FFAR1 (0.46) | CCNCCDK8 | |
| SCHEMBL13680452 | 0.66 | GSK3B (0.61) | ALDH1A1GSK3BKDM4EKMT2AMAPT | |
| SCHEMBL13113429 | 0.66 | HSD17B10 (0.50) | ALDH1A1POLBRAB9AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |