Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922006 | 0.74 | TLR8 (0.37) | MAPTSMN1; SMN2APEX1 | |
| SCHEMBL5898325 | 0.72 | — | — | |
| SCHEMBL4155788 | 0.69 | CHRM2 (0.45) | MAPT | |
| SCHEMBL3923901 | 0.69 | MAPT (0.42) | MAPTSMN1; SMN2 | |
| SCHEMBL183395 | 0.69 | — | — | |
| SCHEMBL1616548 | 0.69 | ALDH1A1 (0.41) | MAPT | |
| SCHEMBL4301123 | 0.67 | — | — | |
| SCHEMBL3906982 | 0.67 | — | — | |
| SCHEMBL14034872 | 0.67 | — | — | |
| SCHEMBL20419311 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |