Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 11/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681369 | 0.86 | MAPT (0.50) | ALDH1A1KDM4EHSD17B10MAPTNPC1 | |
| SCHEMBL13680881 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10MAPTNPC1 | |
| SCHEMBL13680878 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10MAPTNPC1 | |
| SCHEMBL13680882 | 0.83 | KDM4E (0.60) | ALDH1A1KDM4EHSD17B10MAPTNPC1 | |
| SCHEMBL13680892 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10MAPTNPC1 | |
| SCHEMBL13680890 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10MAPTNPC1 | |
| SCHEMBL13680875 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10MAPTNPC1 | |
| SCHEMBL13680898 | 0.81 | MAPK1 (0.43) | ALDH1A1KDM4EHSD17B10MAPTNPC1 | |
| SCHEMBL13680872 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10MAPTNPC1 | |
| SCHEMBL13680999 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |