Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680896 | 0.85 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL20339324 | 0.81 | ALDH1A1 (0.51) | MAPK1KDM4EALDH1A1MAPTDYRK1A | |
| SCHEMBL13680876 | 0.81 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL13680900 | 0.80 | MAPT (0.41) | KDM4EALDH1A1MAPTPKMNPC1 | |
| SCHEMBL13681025 | 0.79 | MAPT (0.38) | MAPK1KDM4EALDH1A1MAPTPKM | |
| SCHEMBL13680899 | 0.78 | CYP2C19 (0.40) | MAPK1KDM4EALDH1A1MAPTPKM | |
| SCHEMBL13680903 | 0.77 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL13680506 | 0.77 | MAPK1 (0.51) | MAPK1KDM4EALDH1A1MAPTPKM | |
| SCHEMBL13681005 | 0.76 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL13680889 | 0.76 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTPKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |